Like writing any code, building PySide applications is all about approaching it in the right way. In the first part of the course we cover the fundamentals necessary to get you building Python GUIs as quickly as possible. By the end of the first part you'll have a running QApplication which we can then customize.
Getting started with PySide
Take your first steps building Python & Qt5 apps with PySide
Start with “Creating your first app with PySide2”